منابع مشابه
Clearance of intravitreal voriconazole.
UNLABELLED Purpose To investigate the elimination rate of voriconazole after intravitreal injection in rabbits. METHODS Intravitreal injections of 35 microg/0.1 mL voriconazole were administered to rabbits. Vitreous and aqueous humor levels of voriconazole were determined at selected time intervals (1, 2, 4, 8, 16, 24, and 48 hours), and the in vitreous half-life was calculated. Four to six e...
متن کاملSafety of intravitreal voriconazole: electroretinographic and histopathologic studies.
PURPOSE Voriconazole, a novel triazole antifungal agent, presents potent activity against a broad spectrum of yeast and molds. To determine whether it could be safely used as an intravitreal agent in the treatment of fungal endophthalmitis, retinal toxicity of voriconazole was examined in a rodent animal model. METHODS Voriconazole solutions were serially diluted and injected intravitreally i...
متن کاملFilamentous fungal endophthalmitis: results of combination therapy with intravitreal amphotericin B and voriconazole
PURPOSE To report outcomes of exogenous fungal endophthalmitis treated with combination of intravitreal antifungal agents. DESIGN Retrospective, non-randomized, interventional, consecutive case series. METHODS Twelve eyes of twelve consecutive cases of filamentous fungal endophthalmitis were treated with a combination of intravitreal amphotericin-B and intravitreal voriconazole (AmB-Vo Regi...
متن کاملFusarium Endophthalmitis following Cataract Surgery: Successful Treatment with Intravitreal and Systemic Voriconazole
Purpose. To report a case of postoperative endophthalmitis caused by Fusarium species successfully treated with intravitreal and systemic voriconazole after treatment failure with amphotericin B. Methods. Clinical case report of a 60-year-old immunocompetent woman who presents with endophthalmitis of unknown origin 4 weeks after uneventful cataract extraction and IOL implantation surgery. IOL e...
متن کاملHallucinations during voriconazole therapy.
As part of a prospective natural history cohort study of voriconazole toxicity, we describe the characteristics of 12 of 72 voriconazole-treated patients who experienced hallucinations from March 2006 through November 2007. Hallucinations associated with voriconazole use are not uncommon. Doctors should be aware of this complication, and the recipients of the drug should be reassured that the h...
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ژورنال
عنوان ژورنال: Archives of Ophthalmology
سال: 2004
ISSN: 0003-9950
DOI: 10.1001/archopht.122.11.1687